DNA on disk

Diagnostic platform and kits in the fields of oncology, neurology, infectious diseases and poverty-related diseases.

One of the main causes of the gap between recent progress in biomedical research in oncology and neurology and the impact on clinical medicine is the sophisticated and quick evolution of devices with complex bioinformatic systems, which are fundamental for genomics.

The objective of the DNA ON DISK project is to research, develop and prototype new low-cost hybrid silicon-plastic devices to bridge that gap, capitalizing on progress in microelectronics, microfluidics, MEMS to develop advanced platforms in in-vitro molecular diagnostics.

These technologies make it possible to generate multiple diagnostic information by individual test and at the same time information on treatment, based on the observed resistance to a drug or on the type of disease identified at DNA level. This feature, associated to the low cost of the device, will certainly contribute to the reduction of healthcare system costs.

This device, together with reagents and software, combines technologies and methodologies in different fields and will certainly be able to bring down existing barriers, thus favouring penetration into clinical medicine and at Points of Care, thus allowing cost reductions.

Project Leader: STMicroelectronics

Partners: Clonit, Fondazione San Raffaele, Consorzio Interuniversitario per le Tecnologie, CNR, Fleming Reasearch, Università degli Studi di Milano

Project Manager: Sabrina Conoci (STMicroelectronics)

Accounting Manager: Anna Leonardi (STMicroelectronics)

Training Manager: Sebastiano Cavallaro (Consiglio Nazionale delle Ricerche)